Forward-imaging swept source coherence tomography using silicon MEMS scanner for high-speed 3-D volumetric imaging

While nonoptical medical imaging techniques such as computed tomography, magnetic-resonance imaging, and ultrasound can be very useful in guiding surgical procedures, they lack the spatial resolution required for revealing tissue microarchitecture, which can be important in time-critical applications, such as staging of tumors.1 In contrast, optical imaging modalities such as confocal, two-photon, and fluorescence microscopy, and optical coherence tomography (OCT) provide depth-resolved imaging even in turbid media, with cellular-level detail.

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